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K-Ras(G12C) Inhibitor 6

CAS No. 2060530-16-5

K-Ras(G12C) Inhibitor 6( K-Ras(G12C) Inhibitor 6 | MDK30165 )

Catalog No. M17423 CAS No. 2060530-16-5

K-Ras(G12C) inhibitor 6 is an irreversible, allosteric inhibitor of the K-Ras(G12C) mutant that causes 100% modification of the protein when used at 10 μM for 24 hours in vitro.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    K-Ras(G12C) Inhibitor 6
  • Note
    Research use only, not for human use.
  • Brief Description
    K-Ras(G12C) inhibitor 6 is an irreversible, allosteric inhibitor of the K-Ras(G12C) mutant that causes 100% modification of the protein when used at 10 μM for 24 hours in vitro.
  • Description
    MDK30165, also known as K-Ras(G12C) Inhibitor 6. It has no formal code name. For the convenience of communication, we name it as MDK30165. It has CAS#2060530-16-5, in which the last 5 digit is used for its code name. K-Ras(G12C) inhibitor 6 is an irreversible, allosteric inhibitor of the K-Ras(G12C) mutant that causes 100% modification of the protein when used at 10 μM for 24 hours in vitro.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    K-Ras(G12C) Inhibitor 6 | MDK30165
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    K-Ras
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    2060530-16-5
  • Formula Weight
    405.33
  • Molecular Formula
    C17H22Cl2N2O3S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Clc1ccc(OCC(=O)N2CCC(NC(=O)CCCS)CC2)c(Cl)c1
  • Chemical Name
    N-(1-(2-(2,4-dichlorophenoxy)acetyl)piperidin-4-yl)-4-mercaptobutanamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hunter JC, Gurbani D, Ficarro SB, Carrasco MA, Lim SM, Choi HG, Xie T, Marto JA, Chen Z, Gray NS, Westover KD. Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):8895-900.
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